Loading...

Are D-manno-configured Amadori products ligands of the bacterial lectin FimH?

The Amadori rearrangement was employed for the synthesis of C-glycosyl-type D-mannoside analogues, namely 1-propargylamino- and 1-phenylamino-1-deoxy-α-D-manno-heptopyranose. They were investigated as ligands of type 1-fimbriated E. coli bacteria by means of molecular docking and bacterial adhesion...

Full description

Saved in:
Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Gloe, Tobias-Elias, Stamer, Insa, Hojnik, Cornelia, Wrodnigg, Tanja M, Lindhorst, Thisbe K
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505182/
https://ncbi.nlm.nih.gov/pubmed/26199665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.123
Tags: Add Tag
No Tags, Be the first to tag this record!