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Are D-manno-configured Amadori products ligands of the bacterial lectin FimH?

The Amadori rearrangement was employed for the synthesis of C-glycosyl-type D-mannoside analogues, namely 1-propargylamino- and 1-phenylamino-1-deoxy-α-D-manno-heptopyranose. They were investigated as ligands of type 1-fimbriated E. coli bacteria by means of molecular docking and bacterial adhesion...

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Bibliografski detalji
Izdano u:Beilstein J Org Chem
Glavni autori: Gloe, Tobias-Elias, Stamer, Insa, Hojnik, Cornelia, Wrodnigg, Tanja M, Lindhorst, Thisbe K
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505182/
https://ncbi.nlm.nih.gov/pubmed/26199665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.123
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