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Are D-manno-configured Amadori products ligands of the bacterial lectin FimH?
The Amadori rearrangement was employed for the synthesis of C-glycosyl-type D-mannoside analogues, namely 1-propargylamino- and 1-phenylamino-1-deoxy-α-D-manno-heptopyranose. They were investigated as ligands of type 1-fimbriated E. coli bacteria by means of molecular docking and bacterial adhesion...
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| Publicado en: | Beilstein J Org Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Beilstein-Institut
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505182/ https://ncbi.nlm.nih.gov/pubmed/26199665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.123 |
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