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Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods
The neuropeptides, orexin A and orexin B (also known as hypocretins), are produced in hypothalamic neurons and belong to ligands for orphan G protein-coupled receptors. Generally, the primary role of orexins is to act as excitatory neurotransmitters and regulate the sleep process. Lack of orexins ma...
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| Publicat a: | Molecules |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6278354/ https://ncbi.nlm.nih.gov/pubmed/30423961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112926 |
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