Profiling donepezil template into multipotent hybrids with antioxidant properties

Alzheimer’s disease is debilitating neurodegenerative disorder in the elderly. Current therapy relies on administration of acetylcholinesterase inhibitors (AChEIs) -donepezil, rivastigmine, galantamine, and N-methyl-d-aspartate receptor antagonist memantine. However, their therapeutic effect is only...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Mezeiova, Eva, Spilovska, Katarina, Nepovimova, Eugenie, Gorecki, Lukas, Soukup, Ondrej, Dolezal, Rafael, Malinak, David, Janockova, Jana, Jun, Daniel, Kuca, Kamil, Korabecny, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009928/
https://ncbi.nlm.nih.gov/pubmed/29529892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1443326
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