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A 7-methoxytacrine–4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication

Chemical warfare agents constitute an increasing threat to both military and civilian populations. Therefore, effective prophylactic approaches are urgently needed. Herein, we present a novel hybrid compound which is able not only to keep acetylcholinesterase resistant to organophosphate (OP) inhibi...

詳細記述

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書誌詳細
出版年:Toxicol Res (Camb)
主要な著者: Nepovimova, E., Korabecny, J., Dolezal, R., Nguyen, T. D., Jun, D., Soukup, O., Pasdiorova, M., Jost, P., Muckova, L., Malinak, D., Gorecki, L., Musilek, K., Kuca, Kamil
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062411/
https://ncbi.nlm.nih.gov/pubmed/30090408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00130k
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