The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

BACKGROUND: Peritoneal dissemination is a critical prognostic factor in ovarian cancer. Although stabilized spheroid formation promotes cancer cell peritoneal dissemination in ovarian cancer, the associated oncogenes are unknown. In this study, we assessed the role of the KRAS oncogene in ovarian ca...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ogishima, Juri, Taguchi, Ayumi, Kawata, Akira, Kawana, Kei, Yoshida, Mitsuyo, Yoshimatsu, Yuki, Sato, Masakazu, Nakamura, Hiroe, Kawata, Yoshiko, Nishijima, Akira, Fujimoto, Asaha, Tomio, Kensuke, Adachi, Katsuyuki, Nagamatsu, Takeshi, Oda, Katsutoshi, Kiyono, Tohru, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278087/
https://ncbi.nlm.nih.gov/pubmed/30509235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4922-4
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