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Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

The Warburg effect is a metabolic hallmark of cancer cells; cancer cells, unlike normal cells, exclusively activate glycolysis, even in the presence of enough oxygen. On the other hand, intratumoral heterogeneity is currently of interest in cancer research, including that involving cancer stem cells...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sato, Masakazu, Kawana, Kei, Adachi, Katsuyuki, Fujimoto, Asaha, Yoshida, Mitsuyo, Nakamura, Hiroe, Nishida, Haruka, Inoue, Tomoko, Taguchi, Ayumi, Takahashi, Juri, Eguchi, Satoko, Yamashita, Aki, Tomio, Kensuke, Wada-Hiraike, Osamu, Oda, Katsutoshi, Nagamatsu, Takeshi, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078095/
https://ncbi.nlm.nih.gov/pubmed/27120812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8947
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