4Mu Decreases CD47 Expression on Hepatic Cancer Stem Cells and Primes a Potent Antitumor T Cell Response Induced by Interleukin-12

The tumor microenvironment (TME) represents a complex interplay between different cellular components, including tumor cells and cancer stem cells (CSCs), with the associated stroma; such interaction promotes tumor immune escape and sustains tumor growth. Several experimental approaches for cancer t...

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Vydáno v:Mol Ther
Hlavní autoři: Rodríguez, Marcelo M., Fiore, Esteban, Bayo, Juan, Atorrasagasti, Catalina, García, Mariana, Onorato, Agostina, Domínguez, Luciana, Malvicini, Mariana, Mazzolini, Guillermo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277513/
https://ncbi.nlm.nih.gov/pubmed/30301668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.09.012
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