4Mu Decreases CD47 Expression on Hepatic Cancer Stem Cells and Primes a Potent Antitumor T Cell Response Induced by Interleukin-12

The tumor microenvironment (TME) represents a complex interplay between different cellular components, including tumor cells and cancer stem cells (CSCs), with the associated stroma; such interaction promotes tumor immune escape and sustains tumor growth. Several experimental approaches for cancer t...

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Foilsithe in:Mol Ther
Main Authors: Rodríguez, Marcelo M., Fiore, Esteban, Bayo, Juan, Atorrasagasti, Catalina, García, Mariana, Onorato, Agostina, Domínguez, Luciana, Malvicini, Mariana, Mazzolini, Guillermo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2018
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277513/
https://ncbi.nlm.nih.gov/pubmed/30301668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.09.012
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