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Developmental regulation of kidney and liver SLC and ABC drug transporters and drug metabolizing enzymes: the role of remote organ communication

INTRODUCTION: The ontogeny of drug transport and metabolism is generally studied independently in tissues, yet in the immediate postnatal period the developmental regulation of transporters and metabolizing enzymes must be coordinated. Using the Remote Sensing and Signaling Hypothesis as a framework...

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Vydáno v:Expert Opin Drug Metab Toxicol
Hlavní autoři: Momper, Jeremiah D, Nigam, Sanjay K
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277044/
https://ncbi.nlm.nih.gov/pubmed/29746174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1473376
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