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Developmental regulation of kidney and liver SLC and ABC drug transporters and drug metabolizing enzymes: the role of remote organ communication

INTRODUCTION: The ontogeny of drug transport and metabolism is generally studied independently in tissues, yet in the immediate postnatal period the developmental regulation of transporters and metabolizing enzymes must be coordinated. Using the Remote Sensing and Signaling Hypothesis as a framework...

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Publicat a:Expert Opin Drug Metab Toxicol
Autors principals: Momper, Jeremiah D, Nigam, Sanjay K
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277044/
https://ncbi.nlm.nih.gov/pubmed/29746174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1473376
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