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Developmental regulation of kidney and liver SLC and ABC drug transporters and drug metabolizing enzymes: the role of remote organ communication

INTRODUCTION: The ontogeny of drug transport and metabolism is generally studied independently in tissues, yet in the immediate postnatal period the developmental regulation of transporters and metabolizing enzymes must be coordinated. Using the Remote Sensing and Signaling Hypothesis as a framework...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Metab Toxicol
Main Authors: Momper, Jeremiah D, Nigam, Sanjay K
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277044/
https://ncbi.nlm.nih.gov/pubmed/29746174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1473376
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