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Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model

Colorectal cancer (CRC) develops from colonic epithelial cells that lose expression of key tumor suppressor genes and/or gain expression of proproliferative and antiapoptotic genes like heat shock protein 70 (Hsp70). Heat shock protein 70 is overexpressed in CRC, but it is not known whether this is...

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Detalles Bibliográficos
Publicado en:Carcinogenesis
Autores principales: Tao, Yun, Messer, Jeannette S., Goss, Kathleen H., Hart, John, Bissonnette, Marc, Chang, Eugene B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276941/
https://ncbi.nlm.nih.gov/pubmed/27207671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw056
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