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Malic Enzyme 1 (ME1) is pro-oncogenic in Apc(Min/+) mice
Cytosolic Malic Enzyme (ME1) provides reduced NADP for anabolism and maintenance of redox status. To examine the role of ME1 in tumor genesis of the gastrointestinal tract, we crossed mice having augmented intestinal epithelial expression of ME1 (ME1-Tg mice) with Apc(Min/+) mice to obtain male Apc(...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155149/ https://ncbi.nlm.nih.gov/pubmed/30250042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32532-w |
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