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Malic Enzyme 1 (ME1) in the Biology of Cancer: It’s not Just Intermediary Metabolism

Malic Enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to pyruvate while concomitantly generating NADPH from NADP. Early studies identified ME1 as a mediator of intermediary metabolism primarily through its participatory roles in lipid and cholesterol biosynthesis. ME1 w...

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Detalhes bibliográficos
Publicado no:J Mol Endocrinol
Main Authors: Simmen, Frank A., Alhallak, Iad, Simmen, Rosalia C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577320/
https://ncbi.nlm.nih.gov/pubmed/33064660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-20-0176
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