Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo

Vitiligo is an autoimmune disease characterized by destruction of melanocytes, leaving 0.5% of the population with progressive depigmentation. Current treatments offer limited efficacy. We report that modified inducible heat shock protein 70 (HSP70i) prevents T cell–mediated depigmentation. HSP70i i...

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Bibliografiset tiedot
Päätekijät: Mosenson, Jeffrey A., Zloza, Andrew, Nieland, John D., Garrett-Mayer, Elizabeth, Eby, Jonathan M., Huelsmann, Erica J., Kumar, Previn, Denman, Cecele J., Lacek, Andrew T., Kohlhapp, Frederick J., Alamiri, Ahmad, Hughes, Tasha, Bines, Steven D., Kaufman, Howard L., Overbeck, Andreas, Mehrotra, Shikhar, Hernandez, Claudia, Nishimura, Michael I., Guevara-Patino, Jose A., Le Poole, I. Caroline
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912753/
https://ncbi.nlm.nih.gov/pubmed/23447019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005127
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