Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle

BACKGROUND: Plasma-derived cell-free tumor DNA (ctDNA) constitutes a potential surrogate for tumor DNA obtained from tissue biopsies. We posit that massively parallel sequencing (MPS) analysis of ctDNA may help define the repertoire of mutations in breast cancer and monitor tumor somatic alterations...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Ann Oncol
Main Authors: De Mattos-Arruda, L, Weigelt, B, Cortes, J, Won, H H, Ng, C K Y, Nuciforo, P, Bidard, F C, Aura, C, Saura, C, Peg, V, Piscuoglio, S, Oliveira, M, Smolders, Y, Patel, P, Norton, L, Tabernero, J, Berger, M F, Seoane, J, Reis-Filho, J S
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276937/
https://ncbi.nlm.nih.gov/pubmed/25009010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdu239
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares