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Regulatory discrimination of mRNAs by FMRP controls mouse adult neural stem cell differentiation

Fragile X syndrome (FXS) is caused by the loss of fragile X mental retardation protein (FMRP), an RNA binding protein whose deficiency impacts many brain functions, including differentiation of adult neural stem cells (aNSCs). However, the mechanism by which FMRP influences these processes remains u...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Botao, Li, Yue, Stackpole, Emily E., Novak, Annie, Gao, Yu, Zhao, Yinghua, Zhao, Xinyu, Richter, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275535/
https://ncbi.nlm.nih.gov/pubmed/30373821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809588115
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