Jatrorrhizine Hydrochloride Suppresses RANKL-Induced Osteoclastogenesis and Protects against Wear Particle-Induced Osteolysis

Wear particle-induced aseptic prosthetic loosening is a major complication associated with total joint arthroplasty (TJA). A growing body of evidence suggests that receptor activator of nuclear factor κ-B ligand (RANKL)-stimulated osteoclastogenesis and bone resorption are responsible for peri-impla...

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Pubblicato in:Int J Mol Sci
Autori principali: Li, Hui, Wang, Jing, Sun, Qiwen, Chen, Gang, Sun, Shengnan, Ma, Xuemei, Qiu, Haiwen, Liu, Xuerong, Xu, Liangyi, Liu, Mei
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275021/
https://ncbi.nlm.nih.gov/pubmed/30469456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113698
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