3D Microfluidic Ex Vivo Culture of Organotypic Tumor Spheroids to Model Immune Checkpoint Blockade

Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy. Indeed, several microdevices are being developed specifically for clinical use to test novel cancer therapeutics. To be effective, these platforms need to replicate the continuous interactions that exist between tu...

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Publicado en:Lab Chip
Autores principales: Aref, Amir R., Campisi, Marco, Ivanova, Elena, Portell, Andrew, Larios, Dalia, Piel, Brandon P., Mathur, Natasha, Zhou, Chensheng, Coakley, Raven Vlahos, Bartels, Alan, Bowden, Michaela, Herbert, Zach, Gilhooley, Sean, Carter, Jacob, Cañadas, Israel, Thai, Tran C., Kitajima, Shunsuke, Chiono, Valeria, Paweletz, Cloud P., Barbie, David A., Kamm, Roger D., Jenkins, Russell W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274590/
https://ncbi.nlm.nih.gov/pubmed/30183789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8lc00322j
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