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Tumor-Derived cGAMP Regulates Activation of the Vasculature
Intratumoral recruitment of immune cells following innate immune activation is critical for anti-tumor immunity and involves cytosolic dsDNA sensing by the cGAS/STING pathway. We have previously shown that KRAS-LKB1 (KL) mutant lung cancer, which is resistant to PD-1 blockade, exhibits silencing of...
שמור ב:
| הוצא לאור ב: | Front Immunol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7507350/ https://ncbi.nlm.nih.gov/pubmed/33013881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02090 |
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