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Tumor-Derived cGAMP Regulates Activation of the Vasculature

Intratumoral recruitment of immune cells following innate immune activation is critical for anti-tumor immunity and involves cytosolic dsDNA sensing by the cGAS/STING pathway. We have previously shown that KRAS-LKB1 (KL) mutant lung cancer, which is resistant to PD-1 blockade, exhibits silencing of...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Campisi, Marco, Sundararaman, Shriram K., Shelton, Sarah E., Knelson, Erik H., Mahadevan, Navin R., Yoshida, Ryohei, Tani, Tetsuo, Ivanova, Elena, Cañadas, Israel, Osaki, Tatsuya, Lee, Sharon Wei Ling, Thai, Tran, Han, Saemi, Piel, Brandon P., Gilhooley, Sean, Paweletz, Cloud P., Chiono, Valeria, Kamm, Roger D., Kitajima, Shunsuke, Barbie, David A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507350/
https://ncbi.nlm.nih.gov/pubmed/33013881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02090
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