3D Microfluidic Ex Vivo Culture of Organotypic Tumor Spheroids to Model Immune Checkpoint Blockade

Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy. Indeed, several microdevices are being developed specifically for clinical use to test novel cancer therapeutics. To be effective, these platforms need to replicate the continuous interactions that exist between tu...

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Pubblicato in:Lab Chip
Autori principali: Aref, Amir R., Campisi, Marco, Ivanova, Elena, Portell, Andrew, Larios, Dalia, Piel, Brandon P., Mathur, Natasha, Zhou, Chensheng, Coakley, Raven Vlahos, Bartels, Alan, Bowden, Michaela, Herbert, Zach, Gilhooley, Sean, Carter, Jacob, Cañadas, Israel, Thai, Tran C., Kitajima, Shunsuke, Chiono, Valeria, Paweletz, Cloud P., Barbie, David A., Kamm, Roger D., Jenkins, Russell W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274590/
https://ncbi.nlm.nih.gov/pubmed/30183789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8lc00322j
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