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Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents

In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal and chemical stimuli were evaluated by tail-clip, hot-plate and acetic acid...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Altıntop, Mehlika Dilek, Can, Özgür Devrim, Demir Özkay, Ümide, Kaplancıklı, Zafer Asım
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273905/
https://ncbi.nlm.nih.gov/pubmed/27490523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21081004
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