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Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents

In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a–s were synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) and modified forced swimming test (MFST). The effects of the compounds on spontaneous locomotor activity were also...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Özdemir, Ahmet, Altıntop, Mehlika Dilek, Kaplancıklı, Zafer Asım, Can, Özgür Devrim, Özkay, Ümide Demir, Turan-Zitouni, Gülhan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272793/
https://ncbi.nlm.nih.gov/pubmed/25658142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022668
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