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Synthesis and Structure-Activity Relationships of Imidazole-Coumarin Conjugates against Hepatitis C Virus
A series of new conjugated compounds with a –SCH(2)– linkage were synthesized by chemical methods from imidazole and coumarin derivatives. The experimental results indicate that of the twenty newly synthesized imidazole–coumarin conjugates, three of them exhibited appealing EC(50) values (5.1–8.4 μM...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6273635/ https://ncbi.nlm.nih.gov/pubmed/26901180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020228 |
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