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New Deferoxamine Glycoconjugates Produced upon Overexpression of Pathway-Specific Regulatory Gene in the Marine Sponge-Derived Streptomyces albus PVA94-07

Activation of silent biosynthetic gene clusters in Streptomyces bacteria via overexpression of cluster-specific regulatory genes is a promising strategy for the discovery of novel bioactive secondary metabolites. This approach was used in an attempt to activate a cryptic gene cluster in a marine spo...

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Опубликовано в: :Molecules
Главные авторы: Sekurova, Olga N., Pérez-Victoria, Ignacio, Martín, Jesús, Degnes, Kristin F., Sletta, Håvard, Reyes, Fernando, Zotchev, Sergey B.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273380/
https://ncbi.nlm.nih.gov/pubmed/27618884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21091131
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