Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta

Cholinesterases and amyloid beta are one of the major biological targets in the search for a new and efficacious treatment of Alzheimer’s disease. The study describes synthesis and pharmacological evaluation of new compounds designed as dual binding site acetylcholinesterase inhibitors. Among the sy...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Hebda, Michalina, Bajda, Marek, Więckowska, Anna, Szałaj, Natalia, Pasieka, Anna, Panek, Dawid, Godyń, Justyna, Wichur, Tomasz, Knez, Damijan, Gobec, Stanislav, Malawska, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273065/
https://ncbi.nlm.nih.gov/pubmed/27023510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040410
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge