Dual Inhibitors of Amyloid-β and Tau Aggregation with Amyloid-β Disaggregating Properties: Extended In Cellulo, In Silico, and Kinetic Studies of Multifunctional Anti-Alzheimer’s Agents

[Image: see text] In Alzheimer’s disease, neurons slowly degenerate due to the accumulation of misfolded amyloid β and tau proteins. In our research, we performed extended studies directed at amyloid β and tau aggregation inhibition using in cellulo (Escherichia coli model of protein aggregation), i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Chem Neurosci
Main Authors: Pasieka, Anna, Panek, Dawid, Szałaj, Natalia, Espargaró, Alba, Więckowska, Anna, Malawska, Barbara, Sabaté, Raimon, Bajda, Marek
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2021
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291496/
https://ncbi.nlm.nih.gov/pubmed/34019757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.1c00235
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki