Neferine Attenuates the Protein Level and Toxicity of Mutant Huntingtin in PC-12 Cells via Induction of Autophagy

Mutant huntingtin aggregation is highly associated with the pathogenesis of Huntington’s disease, an adult-onset autosomal dominant disorder, which leads to a loss of motor control and decline in cognitive function. Recent literature has revealed the protective role of autophagy in neurodegenerative...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Wong, Vincent Kam Wai, Wu, An Guo, Wang, Jing Rong, Liu, Liang, Law, Betty Yuen-Kwan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272412/
https://ncbi.nlm.nih.gov/pubmed/25699594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20033496
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia