Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca(2+)-dependent mechanism

Resistance of cancer cells to chemotherapy is a significant clinical concern and mechanisms regulating cell death in cancer therapy, including apoptosis, autophagy or necrosis, have been extensively investigated over the last decade. Accordingly, the identification of medicinal compounds against che...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Law, Betty Yuen Kwan, Michelangeli, Francesco, Qu, Yuan Qing, Xu, Su-Wei, Han, Yu, Mok, Simon Wing Fai, Dias, Ivo Ricardo de Seabra Rodrigues, Javed, Masood-ul-Hassan, Chan, Wai-Kit, Xue, Wei-Wei, Yao, Xiao-Jun, Zeng, Wu, Zhang, Hui, Wang, Jing-Rong, Liu, Liang, Wong, Vincent Kam Wai
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934498/
https://ncbi.nlm.nih.gov/pubmed/31882989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56675-6
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