Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells

Emerging evidence indicates important protective roles being played by autophagy in neurodegenerative disorders through clearance of aggregate-prone or mutant proteins. In the current study, we aimed to identify autophagy inducers from Chinese medicinal herbs as a potential neuroprotective agent tha...

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Bibliografische gegevens
Hoofdauteurs: Wu, An-Guo, Wong, Vincent Kam-Wai, Xu, Su-Wei, Chan, Wai-Kit, Ng, Choi-In, Liu, Liang, Law, Betty Yuen-Kwan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Molecular Diversity Preservation International (MDPI) 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856081/
https://ncbi.nlm.nih.gov/pubmed/24248062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141122618
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