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Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins

With its traditional use in relieving insomnia and anxiety, our previous study has identified onjisaponin B from Radix Polygalae (RP), as a novel autophagic enhancer with potential neuroprotective effects. In current study, we have further identified a novel active fraction from RP, contains 17 majo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, An-Guo, Kam-Wai Wong, Vincent, Zeng, Wu, Liu, Liang, Yuen-Kwan Law, Betty
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657008/
https://ncbi.nlm.nih.gov/pubmed/26598009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17199
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