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Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells
Resistance of cancer cells to chemotherapy is a significant problem in oncology, and the development of sensitising agents or small-molecules with new mechanisms of action to kill these cells is needed. Autophagy is a cellular process responsible for the turnover of misfolded proteins or damaged org...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076737/ https://ncbi.nlm.nih.gov/pubmed/24981420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05510 |
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