Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms

Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal herbs as potential anti-tumor agents through autophagic induction, which finally lead to autophagy mediated-cell death in apoptosis-resistant ca...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wong, Vincent Kam Wai, Zeng, Wu, Chen, Juan, Yao, Xiao Jun, Leung, Elaine Lai Han, Wang, Qian Qian, Chiu, Pauline, Ko, Ben C. B., Law, Betty Yuen Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462963/
https://ncbi.nlm.nih.gov/pubmed/28642707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00351
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