Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

Previously designed cyclic peptide antagonist c[YYDEGLEE]-NH(2) disrupts the interaction between vascular endothelial growth factor (VEGF) and its receptors (VEGFRs). It represents a promising tool in the fight against cancer and age-related macular degeneration. We described in this paper the optim...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Lei, Gagey-Eilstein, Nathalie, Broussy, Sylvain, Reille-Seroussi, Marie, Huguenot, Florent, Vidal, Michel, Liu, Wang-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270838/
https://ncbi.nlm.nih.gov/pubmed/25264829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules191015391
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