A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition

Angiogenesis is central to the growth of cancers and VEGFR-1/Flt-1 plays an important role during the neovascularization under pathological conditions. We previously founded a VEGFR1 antagonistic peptide, F56, by screening the phage peptide library. We showed that DHFR-F56 chimeric protein displayed...

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Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Zhou, Zheng, Zhao, Chuanke, Wang, Lixin, Cao, Xiaodan, Li, Jian, Huang, Ruijing, Lao, Qiaocong, Yu, Hangping, Li, Yanna, Du, Haiyan, Qu, Like, Shou, Chengchao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2015
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656737/
https://ncbi.nlm.nih.gov/pubmed/26693066
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