A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition

Angiogenesis is central to the growth of cancers and VEGFR-1/Flt-1 plays an important role during the neovascularization under pathological conditions. We previously founded a VEGFR1 antagonistic peptide, F56, by screening the phage peptide library. We showed that DHFR-F56 chimeric protein displayed...

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Détails bibliographiques
Publié dans:Am J Cancer Res
Auteurs principaux: Zhou, Zheng, Zhao, Chuanke, Wang, Lixin, Cao, Xiaodan, Li, Jian, Huang, Ruijing, Lao, Qiaocong, Yu, Hangping, Li, Yanna, Du, Haiyan, Qu, Like, Shou, Chengchao
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2015
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656737/
https://ncbi.nlm.nih.gov/pubmed/26693066
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