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Probing Early Misfolding Events in Prion Protein Mutants by NMR Spectroscopy
The post-translational conversion of the ubiquitously expressed cellular form of the prion protein, PrP(C), into its misfolded and pathogenic isoform, known as prion or PrP(Sc), plays a key role in prion diseases. These maladies are denoted transmissible spongiform encephalopathies (TSEs) and affect...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270549/ https://ncbi.nlm.nih.gov/pubmed/23966072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18089451 |
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