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Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior. The solution phase approach was tedious and involved cyclization of a ridged heterocyclic precursor, while solid pha...
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| Publicado no: | Molecules |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6269862/ https://ncbi.nlm.nih.gov/pubmed/23325099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18011111 |
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