BCR-ABL1 genomic DNA PCR response kinetics during first-line imatinib treatment of chronic myeloid leukemia

Accurate quantification of minimal residual disease (MRD) during treatment of chronic myeloid leukemia (CML) guides clinical decisions. The conventional MRD method, RQ-PCR for BCR-ABL1 mRNA, reflects a composite of the number of circulating leukemic cells and the BCR-ABL1 transcripts per cell. BCR-A...

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Udgivet i:Haematologica
Main Authors: Pagani, Ilaria S., Dang, Phuong, Kommers, Ivar O., Goyne, Jarrad M., Nicola, Mario, Saunders, Verity A., Braley, Jodi, White, Deborah L., Yeung, David T., Branford, Susan, Hughes, Timothy P., Ross, David M.
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6269287/
https://ncbi.nlm.nih.gov/pubmed/29976745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.189787
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