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Synthesis and Biological Evaluation of Thiophene Derivatives as Acetylcholinesterase Inhibitors
A series of new thiophene derivatives has been synthesized using the Gewald protocol. The acetylcholinesterase inhibition activity was assayed according to Ellman’s method using donepezil as reference. Some of the compounds were found to be more potent inhibitors than the reference. 2-(2-(4-(4-Metho...
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| Publicado en: | Molecules |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6268334/ https://ncbi.nlm.nih.gov/pubmed/22692245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17067217 |
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