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Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors

New series of indole derivatives analogous to donepezil, a well known anti-Alzheimer and acetylcholinesterase inhibitor drug, was synthesized. A full chemical characterization of the new compounds is provided. Biological evaluation of the new compounds as acetylcholinesterase inhibitors was performe...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ismail, Mohamed M., Kamel, Mona M., Mohamed, Lamia W., Faggal, Samar I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268345/
https://ncbi.nlm.nih.gov/pubmed/22534665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17054811
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