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Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies

A new series of 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N′-[(E)-(substituted phenyl) methylidene] acetohydrazide derivatives (S1–S18) were synthesized and evaluated for their anti-inflammatory activity, analgesic activity, ulcerogenic activity, lipid peroxidation, ulcer index and cyclooxygenase express...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Bhat, Mashooq Ahmad, Al-Omar, Mohamed A., Raish, Mohammad, Ansari, Mushtaq Ahmad, Abuelizz, Hatem A., Bakheit, Ahmed H., Naglah, Ahmed M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100013/
https://ncbi.nlm.nih.gov/pubmed/29882911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23061250
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