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Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5-a]pyrimidines

Pyrazolo[1,5-a]pyrimidines 5a–c, 9a–c and 13a–i were synthesized for evaluation of their in vitro antimicrobial properties against some microorganisms and their immunomodulatory activity. The biological activities of pyrazolo[1,5-a]pyrimidines showed that the pyrazolo[1,5-a]pyrimidines (5c, 9a, 9c,...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Naglah, Ahmed M., Askar, Ahmed A., Hassan, Ashraf S., Khatab, Tamer K., Al-Omar, Mohamed A., Bhat, Mashooq A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144935/
https://ncbi.nlm.nih.gov/pubmed/32245177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061431
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