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Synthesis and Modifications of Phosphinic Dipeptide Analogues

Pseudopeptides containing the phosphinate moiety (-P(O)(OH)CH(2)-) have been studied extensively, mainly as transition state analogue inhibitors of metalloproteases. The key synthetic aspect of their chemistry is construction of phosphinic dipeptide derivatives bearing appropriate side-chain substit...

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Detalhes bibliográficos
Publicado no:Molecules
Autor principal: Mucha, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268094/
https://ncbi.nlm.nih.gov/pubmed/23154272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules171113530
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