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Ozone induces autophagy in rat chondrocytes stimulated with IL-1β through the AMPK/mTOR signaling pathway

BACKGROUND: Ozone injection is generally used for the management of pain in diseases such as osteoarthritis (OA). Recent studies have shown that reduced autophagy in chondrocytes plays an important role in the development of OA. The purpose of this study was to determine whether ozone treats OA by i...

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Vydáno v:J Pain Res
Hlavní autoři: Zhao, Xu, Li, Yun, Lin, Xiaowen, Wang, Junnan, Zhao, Xuejun, Xie, Juntian, Sun, Tao, Fu, Zhijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267635/
https://ncbi.nlm.nih.gov/pubmed/30568481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S183594
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