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Tailoring the AAV2 capsid vector for bone-targeting
BACKGROUND: Targeting specific tissues remains a major challenge to the promise of gene therapy. For example, several strategies have failed to target adeno-associated virus 2 (AAV2) vectors, to bone. We have evaluated in vitro and in vivo the affinity of an AAV2 vector to bone matrix, hydroxyapatit...
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| 出版年: | Pediatr Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6266866/ https://ncbi.nlm.nih.gov/pubmed/30323349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41390-018-0095-8 |
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