Chargement en cours...
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism
The histone methyltransferase Dot1 is conserved from yeast to human and methylates lysine 79 of histone H3 (H3K79) on the core of the nucleosome. H3K79 methylation by Dot1 affects gene expression and the response to DNA damage, and is enhanced by monoubiquitination of the C-terminus of histone H2B (...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
|---|---|
| Auteurs principaux: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6265471/ https://ncbi.nlm.nih.gov/pubmed/30203048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky801 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|