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Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

Given the frequent misregulation of chromatin in cancer, it is important to understand the cellular mechanisms that regulate chromatin structure. However, systematic screening for epigenetic regulators is challenging and often relies on laborious assays or indirect reporter read-outs. Here we descri...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Vlaming, Hanneke, Molenaar, Thom M, van Welsem, Tibor, Poramba-Liyanage, Deepani W, Smith, Desiree E, Velds, Arno, Hoekman, Liesbeth, Korthout, Tessy, Hendriks, Sjoerd, Maarten Altelaar, AF, van Leeuwen, Fred
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179194/
https://ncbi.nlm.nih.gov/pubmed/27922451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18919
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