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Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms

The nucleolus, the site for ribosome biogenesis contains hundreds of proteins and several types of RNA. The functions of many non-ribosomal nucleolar proteins are poorly understood, including Surfeit locus protein 6 (SURF6), an essential disordered protein with roles in ribosome biogenesis and cell...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Ferrolino, Mylene C., Mitrea, Diana M., Michael, J. Robert, Kriwacki, Richard W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265330/
https://ncbi.nlm.nih.gov/pubmed/30498217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07530-1
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