Composition dependent thermodynamics of intracellular phase separation

Intracellular bodies such as nucleoli, Cajal bodies, and various signaling assemblies, represent membraneless organelles, or condensates, that form via liquid-liquid phase separation (LLPS)(1,2). Biomolecular interactions, particularly homotypic interactions mediated by self-associating intrinsicall...

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Udgivet i:Nature
Main Authors: Riback, Joshua A., Zhu, Lian, Ferrolino, Mylene C., Tolbert, Michele, Mitrea, Diana M., Sanders, David W., Wei, Ming-Tzo, Kriwacki, Richard W., Brangwynne, Clifford P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733533/
https://ncbi.nlm.nih.gov/pubmed/32405004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2256-2
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